M00000832
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ISO TR 14735 1st Edition, April 15, 2013 Cosmetics - Analytical methods - Nitrosamines: Technical guidance document for minimizing and determining N-nitrosamines in cosmetics
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Availability date: 07/13/2021
Description / Abstract:
This Technical Reportaims to contribute to providing
general advice on strategies that can be adopted to minimize the
likelihood of N-nitrosamine formation in cosmetic products and
provide a description of the analytical methodologies available for
the reliable determination of N-nitrosamines in cosmetic products.
It also seeks to provide some insight into the relevance and
limitations of each of the methods described and finally provide an
analytical approach for the analysis of N-nitrosamines in cosmetic
products and raw materials.
This Technical Reportcovers the reduction or elimination
of adventitious nitrite sources, reduction or elimination of
secondary amino sources, incorporation of inhibitors to
N-nitrosamine formation and analytical methodologies for total
N-nitroso compounds and specific methods for
N-nitrosodiethanolamine (NDELA).